Bio: Dr. Jed W. Fahey M.S., Sc.D.
Director of the Brassica Chemoprotection Laboratory
Faculty Research Associate, Dept. of Pharmacology, Johns Hopkins University School of Medicine
Dr. Jed W. Fahey M.S., Sc.D. is a Faculty Research Associate in the Department of
Pharmacology, Laboratory of Molecular Pharmacology at the
Johns Hopkins University School of Medicine.
He is also a plant physiologist who manages Johns Hopkins University's
Brassica Chemoprotection Laboratory, where he has been involved in
developing cruciferous plants as chemoprotective agents.
In recent years, Dr. Fahey's work at the Brassica Chemoprotection
Laboratory led to the discovery that broccoli sprouts are an
exceptionally rich source of enzyme inducers, which help to detoxify
carcinogens. The research findings were published in the 1997
Proceedings of the National Academy of Sciences USA.
Dr. Fahey has been an invited lecturer of various classes at the
University of Maryland, Texas A&M University, University of Maryland
School of Medicine and Johns Hopkins School of Public Health. He also
has been an invited speaker at numerous international academic and
business symposia including Seed Technology Workshops, International
Horticultural Society Symposia, the International Symposium on
Brassicas, the Moet-Hennessey Colloquium on Advanced Technology & Plant
Breeding Strategy and the CNRS Antioxidant and Health Symposium.
Dr. Fahey is the author of numerous book chapters, technical
publications and patents, including patented methods for deliberately
inoculating grain seeds with beneficial bacteria, and for the production
of dwarf rice plants.
Dr. Fahey graduated from Johns Hopkins University in 1975 and then
earned a Master of Science degree in botany from the University of
Maryland, and a doctorate in human nutrition from the Johns Hopkins
University School of Public Health.
Dr. Fahey also teaches about phytochemicals via telelink at
Texas A&M University
and has been invited to lecture in such places as Germany, Shanghai,
New Zealand and Japan.
Contact Information
Dr. Fahey receives mail at:
Department of Pharmacology
Johns Hopkins University School of Medicine
Wood Basic Science Building, Room 406
725 North Wolfe Street
Baltimore, Maryland 21205
Email: JFahey@jhmi.edu
Patents
- US 5,968,505: Cancer chemoprotective food products
- US 5,968,567: Method of preparing a food product from cruciferous sprouts
- US 5,725,895: Method of preparing a food product from cruciferous seeds
- US 6,242,018: Cancer Chemoprotective food products
- US 6,177,122: Cancer Chemoprotective food products
- US 5,415,672: Delivery of beneficial clavibacter microorganisms to seeds and plants
- US 5,157,207: Modified plant containing a bacterial insculant
- US 6,521,818: Development of novel highly chemoprotectant crucifer germplasm
- US 6,737,441: Treatment of helicobacter with isothiocyanates
Some Related Papers
- Dietary phytochemical delivery: Glucosinolates/isothiocyanates.
- Fahey, J.W. (2002) Nutrition Today 37(5): 214-217.
- Influence of temperature and ontogeny on the levels of glucosinolates in broccoli (Brassica oleracea var. italica) sprouts and their effect on the induction of mammalian Phase 2 enzymes.
- Pereira FM, Rosa E., Fahey JW, Stephenson KK, Carvalho R & Aires A. (2002)
J. Agric. Food Chem. 50: 6239-6244.
- Urinary excretion of dithiocarbamates and self-reported Cruciferous vegetable intake: Application of the 'Method of Triads' to a food-specific biomarker.
- Fowke, J.H., J.R. Hebert & J.W. Fahey. (2002)
Pub. Health Nutr. 5(6): 791-799.
- "Brassicas" in Encyclopedia of Food Sciences and Nutrition
- Fahey, J.W. (2003), Eds. B. Caballero, L.C. Trugo & P.M. Finglas,
Academic Press, London. pp. 606-613.
- Genetic and environmental effects on glucosinolate content and chemoprotective potency of broccoli.
- Farnham MW, PE Wilson, KK Stephenson & JW Fahey. (2004) Plant Breeding 123: 60-65.
- The "Prochaska" microtiter plate bioassay for inducers of NQO1.
- Fahey JW, AT Dinkova-Kostova, P Talalay (2004)
Chapter 14 in Methods in Enzymology, Vol. 382, Part B, pp. 243-258
(Eds.) H. Sies & L. Packer, Elsevier Science, San Diego, CA.
- Sulforaphane inhibits
extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and
prevents benzo[a]pyrene-induced stomach tumors
- Proc. Natl. Acad. Sci. USA, Vol. 99, Issue 11,
pp. 7610-7615, May 28, 2002
- The chemical diversity and distribution of glucosinolates and isothiocyanates among plants
- Phytochemistry 2001, 56:5-51.
- Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes.
- Food Chem Toxicol 1999 Sep-Oct;37(9-10):973-9
- Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens
- Proc Natl Acad Sci USA 1997 Sep 16;94(19):10367-72
- Chemoprotection against cancer by phase 2 enzyme induction.
- Toxicol Lett 1995 Dec;82-83:173-9
